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RAGE: A Multi-Ligand Receptor Unveiling Novel Insights in Health and Disease

22 May 2010

Abstract excerpt

Receptor for advanced glycation end products (RAGE) is expressed in a range of cell types such as endothelial cells, smooth muscle cells, mesangial cells, mononuclear phagocytes and certain neurons. It is a multi-ligand receptor and a member of the immunoglobulin superfamily of cell surface molecules. Its repertoire of ligands includes advanced glycation end products (AGEs), amyloid fibrils, amphoterin and...

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PMID: 20459381
DOI: 10.2174/092986710791331086

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