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RAGE: The Beneficial and Deleterious Effects by Diverse Mechanisms of Actions

1 Feb 2011

Abstract excerpt

Receptor for advanced glycation endproducts (RAGE) is a transmembrane protein that belongs to the immunoglobulin superfamily. RAGE is expressed ubiquitously-high in lung and moderate to low in a wide range of cells-in a tightly regulated manner at various stages of development. RAGE is a pattern recognition receptor that binds to multiple ligands, including amphoterin, members of the S100/calgranulin family, the...

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PMID: 21347704
DOI: 10.1007/s10059-011-0030-x

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