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Article

An Efficient Intestinal Organoid System of Direct Sorting to Evaluate Stem Cell Competition in Vitro

30 Dec 2019

Abstract excerpt

Abstract Stem cell competition could shed light on the tissue-based quality control mechanism that prevents carcinogenesis. To quantitatively evaluate stem cell competition in vitro, we developed a two-color intestinal organoid forming system. First, we improved a protocol of culturing organoids from intestinal leucine-rich-repeat containing G-protein-coupled receptor 5 (Lgr5)- enhanced green fluorescent protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31889051
DOI: 10.1038/s41598-019-55824-1

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