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Article

The role of backward cell migration in two-hit mutants' production in the stem cell niche.

PloS one - 1 Jan 2017

Bollas Audrey, Shahriyari Leili

Abstract excerpt

It has been discovered that there are two stem cell groups in the intestinal crypts: central stem cells (CeSCs), which are at the very bottom of the crypt, and border stem cells (BSCs), which are located between CeSCs and transit amplifying cells (TAs). Moreover, backward cell migration from BSCs to CeSCs has been observed. Recently, a bi-compartmental stochastic model, which includes CeSCs and BSCs, has been...

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Identifiers

PMID: 28931019
DOI: 10.1371/journal.pone.0184651
PMCID: PMC5607144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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