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Bone marrow-derived cells fuse with normal and transformed intestinal stem cells

10 Apr 2006

Abstract excerpt

Transplanted adult bone marrow-derived cells (BMDCs) have been shown to adopt the phenotype and function of several nonhematopoietic cell lineages and promote tumorigenesis. Beyond its cancer enhancing potential, cell fusion has recently emerged as an explanation of how BMDCs regenerate diseased heptocytes, contribute to Purkinje neurons and skeletal and cardiac muscle cells, and participate in skin and heart...

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PMID: 16606845
DOI: 10.1073/pnas.0508593103

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