Article
A Comprehensive Genome-Wide and Phenome-Wide Examination of BMI and Obesity in a Northern Nevadan Cohort.
G3 (Bethesda, Md.) - 6 Feb 2020
Schlauch Karen A, Read Robert W, Lombardi Vincent C, Elhanan Gai, Metcalf William J, Slonim Anthony D, Grzymski Joseph J
Abstract excerpt
The aggregation of Electronic Health Records (EHR) and personalized genetics leads to powerful discoveries relevant to population health. Here we perform genome-wide association studies (GWAS) and accompanying phenome-wide association studies (PheWAS) to validate phenotype-genotype associations of BMI, and to a greater extent, severe Class 2 obesity, using comprehensive diagnostic and clinical data from the EHR...
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