Article
A genome-wide association study on obesity and obesity-related traits.
PloS one - 28 Apr 2011
Wang Kai, Li Wei-Dong, Zhang Clarence K, Wang Zuoheng, Glessner Joseph T, Grant Struan F A, Zhao Hongyu, Hakonarson Hakon, Price R Arlen
Abstract excerpt
Large-scale genome-wide association studies (GWAS) have identified many loci associated with body mass index (BMI), but few studies focused on obesity as a binary trait. Here we report the results of a GWAS and candidate SNP genotyping study of obesity, including extremely obese cases and never overweight controls as well as families segregating extreme obesity and thinness. We first performed a GWAS on 520 cases...
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