Article
The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study.
Diabetes - 1 May 2013
Graff Mariaelisa, Gordon-Larsen Penny, Lim Unhee, Fowke Jay H, Love Shelly-Ann, Fesinmeyer Megan, Wilkens Lynne R, Vertilus Shawyntee, Ritchie Marilyn D, Prentice Ross L, Pankow Jim, Monroe Kristine, Manson JoAnn E, Le Marchand Loïc, Kuller Lewis H, Kolonel Laurence N, Hong Ching P, Henderson Brian E, Haessler Jeff, Gross Myron D, Goodloe Robert, Franceschini Nora, Carlson Christopher S, Buyske Steven, Bůžková Petra, Hindorff Lucia A, Matise Tara C, Crawford Dana C, Haiman Christopher A, Peters Ulrike, North Kari E
Abstract excerpt
Evidence is limited as to whether heritable risk of obesity varies throughout adulthood. Among >34,000 European Americans, aged 18-100 years, from multiple U.S. studies in the Population Architecture using Genomics and Epidemiology (PAGE) Consortium, we examined evidence for heterogeneity in the associations of five established obesity risk variants (near FTO, GNPDA2, MTCH2, TMEM18, and NEGR1) with BMI across...
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