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Article

Functional Polymorphisms and Gene Expression of TLR9 Gene as Protective Factors for Nasopharyngeal Carcinoma Severity and Progression.

Journal of immunology research - 1 Jan 2019

Yosra Macherki, Sameh Souissi, Randa Ghedira, Yassmine Remadi, Sallouha Gabbouj, Nadia Bouzid, Noureddine Bouaouina, Abdelfattah Zakhama, Elham Hassen

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is a disease that is closely associated with EBV infection. Toll-like receptor 9 is an important factor mediating the interaction between EBV and the host immune response. Any genetic (single nucleotide polymorphisms, SNPs) or expression variation in TLR9 gene may modify the ability of the receptor to respond correctly to viral infection as in NPC. This study is aimed at evaluating...

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Identifiers

PMID: 31886298
DOI: 10.1155/2019/2826563
PMCID: PMC6899320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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