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Article

Impact of toll-like receptor 4 variations on nasopharyngeal carcinoma risk and survival in tunisian population.

La Tunisie medicale - 5 Feb 2024

Ben Chaaben Arij, Ayadi Imen, Abaza Hejer, Baroudi Olfa, Douik Hayet, Harzallah Latifa, Bouassida Jihen, Bouckouaci Wahid, Guemira Fethi, Mankai Amani, Kharrat Maher, Tamouza Ryad

Abstract excerpt

INTRODUCTION: The Toll-like receptor 4 (TLR4), an important member of the host's innate immune response, is coded by a polymorphic gene. This polymorphism could be a predisposing factor for NasoPharyngeal Carcinoma (NPC). AIM: To determine the association between TLR4 gene polymorphisms and the susceptibility to NPC in a cohort of Tunisian affected patients. METHODS: Genomic DNAs from 245 unrelated patients...

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Identifiers

PMID: 38567476
DOI: 10.62438/tunismed.v102i2.4270
PMCID: PMC11358798

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