Article
Polymorphisms of Toll-like receptor 9 are associated with nasopharyngeal carcinoma susceptibility.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2014
Dai Qiong, Li Xing Pu, Chai Li, Long Han An, Yang Zhi Hui
Abstract excerpt
Toll-like receptor 9 (TLR9) plays a pivotal role in sensing a wide range of pathogens, including bacteria, fungi, and viruses. A dysregulation of TLR9 signaling may contribute to a higher risk of developing cancers. A hospital-based case-control study, including 356 nasopharyngeal carcinoma (NPC) cases and 356 controls, was conducted to assess the relationship between TLR9 -1237T/C, -1486T/C, and 2848G/A...
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