Article
Impact of TLR9and TLR7 gene polymorphisms on prognosis and survival of patients with oral squamous cell carcinoma.
Biomolecules & biomedicine - 17 Oct 2024
Obrenović Miroslav, Šupić Gordana, Miyabe Satoru, Mladenović Irena, Kozomara Ružica, Jović Saša, Petković Ćurčin Aleksandra, Štefik Debora, Stosić Srboljub, Vukomanović Đurđević Biserka
Abstract excerpt
Despite significant efforts in developing new diagnostic and therapeutic modalities, oral squamous cell carcinomas (OSCCs) still exhibit a high recurrence rate, a low five-year survival rate, and an increasing prevalence. Toll-like receptors (TLRs), which initiate and perpetuate immune mechanisms upon activation, have been linked to immune surveillance and the antitumor immune response. The aim of this study was...
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