Article
Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population.
BMC cancer - 17 Oct 2007
He Jun-Fang, Jia Wei-Hua, Fan Qin, Zhou Xin-Xi, Qin Hai-De, Shugart Yin Yao, Zeng Yi-Xin
Abstract excerpt
BACKGROUND: Nasopharyngeal carcinoma is endemic in Southern China, displays a strong relationship with genetic susceptibility and associates with Epstein-Barr virus infection. Toll-like receptor 3 (TLR3) plays an important role in the antivirus response. Therefore, we examined the association between TLR3 gene polymorphisms and NPC susceptibility. METHODS: We performed a case-control study of 434 NPC cases and...
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