Article
Isolation, Transfection, and Culture of Primary Human Monocytes.
Journal of visualized experiments : JoVE - 16 Dec 2019
Plaisance-Bonstaff Karlie, Faia Celeste, Wyczechowska Dorota, Jeansonne Duane, Vittori Cecilia, Peruzzi Francesca
Abstract excerpt
Human immunodeficiency virus (HIV) remains a major health concern despite the introduction of combined antiretroviral therapy (cART) in the mid-1990s. While antiretroviral therapy efficiently lowers systemic viral load and restores normal CD4+ T cell counts, it does not reconstitute a completely functional immune system. A dysfunctional immune system in HIV-infected individuals undergoing cART may be...
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