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Decades Long Involvement of THP-1 Cells as a Model for Macrophage Research: A Comprehensive Review

27 Apr 2024

Abstract excerpt

models for examining macrophage behavior under controlled conditions. The THP-1 cell line has become a significant and widely employed tool in macrophage research within these models. Originating from the peripheral blood of individuals with acute monocytic leukemia, this human monocytic cell line can undergo transformation into macrophage-like cells, closely mirroring primary human macrophages when exposed to...

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PMID: 38676532
DOI: 10.2174/0118715230294413240415054610

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