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Article

Characterization of Restrictions to Human Immunodeficiency Virus Type 1 Infection of Monocytes

28 Apr 2004

Abstract excerpt

Tissue macrophages are an important cellular reservoir for replication of human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus. In vitro, the ability of macrophages to support viral replication is differentiation dependent in that precursor monocytes are refractory to infection. There is, however, no consensus as to the exact point at which infection is restricted in monocytes. We have...

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Identifiers

PMID: 15113933
DOI: 10.1128/jvi.78.10.5523-5527.2004

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