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Article

Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac: the Aneurysm-Express Biobank Cohort.

Scientific reports - 27 Dec 2019

van Laarhoven Constance J H C M, van Setten Jessica, van Herwaarden Joost A, Pasterkamp Gerard, de Kleijn Dominique P V, de Borst Gert J, van der Laan Sander W

Abstract excerpt

Recent genome-wide association studies (GWAS) have discovered ten genetic risk variants for abdominal aortic aneurysms (AAA). To what extent these genetic variants contribute to the pathology of aneurysms is yet unknown. The present study aims to investigate whether genetic risk variants are associated with three clinical features: diameter of aneurysm sac, type of artery and aneurysm related-symptoms in aortic...

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Identifiers

PMID: 31882626
DOI: 10.1038/s41598-019-56230-3
PMCID: PMC6934821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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