Article
Novel genetic mechanisms for aortic aneurysms.
Current atherosclerosis reports - 1 Jul 2010
Tromp Gerard, Kuivaniemi Helena, Hinterseher Irene, Carey David J
Abstract excerpt
Aortic aneurysms occur in the thoracic and abdominal sections of the aorta and are a deadly late-age-at-onset disease with complex pathobiology. Currently, the number of published genome-wide analyses including microarray-based expression profiling, DNA linkage studies, and genetic association studies is still limited and it is difficult to make generalizations about the disease pathogenesis or genetic risk...
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