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Linking single nucleotide polymorphisms to signaling blueprints in abdominal aortic aneurysms.

Scientific reports - 5 Dec 2022

Lim Chrysania, Pratama Muhammad Yogi, Rivera Cristobal, Silvestro Michele, Tsao Philip S, Maegdefessel Lars, Gallagher Katherine A, Maldonado Thomas, Ramkhelawon Bhama

Abstract excerpt

Abdominal aortic aneurysms (AAA) is a multifactorial complex disease with life-threatening consequences. While Genome-wide association studies (GWAS) have revealed several single nucleotide polymorphisms (SNPs) located in the genome of individuals with AAA, the link between SNPs with the associated pathological signals, the influence of risk factors on their distribution and their combined analysis is not fully...

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Aortic Aneurysm, Abdominal
Gene Frequency
Genetic Predisposition to Disease
Genome-Wide Association Study
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36470918
DOI: 10.1038/s41598-022-25144-y
PMCID: PMC9722707

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