Article

AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm

2023-08-25

Abstract excerpt

<h4>Background</h4> Thoracic aortic disease is an important cause of morbidity and mortality in the US, and aortic diameter is a heritable contributor to risk. Could a polygenic prediction of ascending aortic diameter improve detection of aortic aneurysm? <h4>Methods</h4> Deep learning was used to measure ascending thoracic aortic diameter in 49,939 UK Biobank participants. A genome-wide association study (GWAS) w...

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Literature Corpus work: 09467dd6-2499-5bba-8b93-abe028d8b03c
DOI: 10.1101/2023.08.23.23294513

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