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Article

Roles of the highly conserved amino acids in the second receptor binding site of the Newcastle disease virus HN protein

1 Dec 2019

Abstract excerpt

BACKGROUND: The paramyxovirus haemagglutinin-neuraminidase (HN) is a multifunctional protein that is responsible for attachment to receptors, removal of receptors from infected cells to prevent viral self-aggregation (neuraminidase, NA) and fusion promotion. It is commonly accepted that there are two receptor binding sites in the globular head of HN, and the second receptor binding site is only involved in the...

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PMID: 31881976
DOI: 10.1186/s12985-019-1273-y

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