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Article

Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk.

Proceedings of the National Academy of Sciences of the United States of America - 6 Sept 2011

Yuan Ping, Swanson Kurt A, Leser George P, Paterson Reay G, Lamb Robert A, Jardetzky Theodore S

Abstract excerpt

The paramyxovirus hemagglutinin-neuraminidase (HN) protein plays multiple roles in viral entry and egress, including binding to sialic acid receptors, activating the fusion (F) protein to activate membrane fusion and viral entry, and cleaving sialic acid from carbohydrate chains. HN is an oligomeric integral membrane protein consisting of an N-terminal transmembrane domain, a stalk region, and an enzymatically...

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Identifiers

PMID: 21873198
DOI: 10.1073/pnas.1111691108
PMCID: PMC3169104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk.PMID 21873198Read ↗

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