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Article

A second receptor binding site on human parainfluenza virus type 3 hemagglutinin-neuraminidase contributes to activation of the fusion mechanism.

Journal of virology - 1 Apr 2007

Porotto Matteo, Fornabaio Micaela, Kellogg Glen E, Moscona Anne

Abstract excerpt

The hemagglutinin-neuraminidase (HN) protein of paramyxoviruses carries out three discrete activities that each affect the ability of HN to promote viral fusion and entry: receptor binding, receptor cleaving (neuraminidase), and triggering of the fusion protein. The interrelationship between the receptor binding and fusion-triggering functions of HN has not been clear. For human parainfluenza type 3 (HPIV3), one...

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Identifiers

PMID: 17229690
DOI: 10.1128/JVI.02617-06
PMCID: PMC1866072

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Source receipt: pubmed, retrieved 7 Sept 2026.

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