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Article

Two single amino acid substitutions in the intervening region of Newcastle disease virus HN protein attenuate viral replication and pathogenicity.

Scientific reports - 12 Aug 2015

Liu Bin, Ji Yanhong, Lin Zhongqing, Fu Yuguang, Muhammad Dafallah Rihab, Zhu Qiyun

Abstract excerpt

Among the proteins encoded by Newcastle disease virus (NDV), the attachment protein (HN) is an important determinant of virulence and pathogenicity. HN has been molecularly characterized at the protein level; however, the relationship between the molecular character of HN and the animal pathotype it causes has not been well explored. Here, we revisited the intervening region (IR) of the HN stalk and extended the...

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Identifiers

PMID: 26267791
DOI: 10.1038/srep13038
PMCID: PMC4533526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two single amino acid substitutions in the intervening region of Newcastle disease virus HN protein attenuate viral replication and pathogenicity.PMID 26267791Read ↗

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