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Article

Mutation at residue 523 creates a second receptor binding site on human parainfluenza virus type 1 hemagglutinin-neuraminidase protein.

Journal of virology - 1 Sept 2006

Bousse Tatiana, Takimoto Toru

Abstract excerpt

The paramyxovirus hemagglutinin-neuraminidase (HN) is a multifunctional protein mediating hemagglutination (HA), neuraminidase (NA), and fusion promotion activities. It has been a matter of debate whether HN contains combined or separate sites for HA and NA activities. To clear the issue, we determined the presence of the second binding site on human parainfluenza virus (hPIV) type 1, 2, and 3 and Sendai virus...

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Identifiers

PMID: 16940513
DOI: 10.1128/JVI.00969-06
PMCID: PMC1563932

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Source receipt: pubmed, retrieved 7 Sept 2026.

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