Article
Alcoholism is associated with GALR3 but not two other galanin receptor genes.
Genes, brain, and behavior - 1 Jul 2007
Belfer I, Hipp H, Bollettino A, McKnight C, Evans C, Virkkunen M, Albaugh B, Max M B, Goldman D, Enoch M A
Abstract excerpt
The neuropeptide galanin is widely expressed in the periphery and the central nervous system and mediates diverse physiological processes and behaviors including alcohol abuse, depression and anxiety. Four genes encoding galanin and its receptors have been identified (GAL, GALR1, GALR2 and GALR3). Recently we found that GAL haplotypes were associated with alcoholism, raising the possibility that genetic variation...
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