Article
IDH2 Mutation Analysis in Undifferentiated and Poorly Differentiated Sinonasal Carcinomas for Diagnosis and Clinical Management.
The American journal of surgical pathology - 1 Mar 2020
Riobello Cristina, López-Hernández Alejandro, Cabal Virginia N, García-Marín Rocío, Suárez-Fernández Laura, Sánchez-Fernández Paula, Vivanco Blanca, Blanco Verónica, López Fernando, Franchi Alessandro, Llorente José L, Hermsen Mario A
Abstract excerpt
A large number of tumor types arise from the mucosa of the sinonasal cavities. Although presenting clinically distinct behavior, due to poorly differentiated histologic features, they can be difficult to classify correctly. Our aim was to investigate whether IDH2 and IDH1 mutations may be specific to a subset of undifferentiated and poorly differentiated sinonasal carcinomas. A total of 125 tumor samples of 7...
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