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Article

Methylation Drivers and Prognostic Implications in Sinonasal Poorly Differentiated Carcinomas

8 Oct 2021

Abstract excerpt

Background: Poorly differentiated sinonasal carcinomas (PDSNCs) are rare and aggressive malignancies, which include squamous cell carcinoma (SCC), sinonasal undifferentiated carcinoma (SNUC), and neuroendocrine carcinomas (NEC). Several epigenetic markers have been suggested to support the histopathological classification, predict prognosis, and guide therapeutic decision. Indeed, molecularly distinct subtypes of...

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PMID: 34638515
DOI: 10.3390/cancers13195030

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