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Article

Prediction and Structural Comparison of Deleterious Coding Nonsynonymous Single Nucleotide Polymorphisms (nsSNPs) in Human LEP Gene Associated with Obesity.

BioMed research international - 1 Jan 2019

Bouafi Hind, Bencheikh Sara, Mehdi Krami A L, Morjane Imane, Charoute Hicham, Rouba Hassan, Saile Rachid, Benhnini Fouad, Barakat Abdelhamid

Abstract excerpt

Leptin is a peptide hormone that regulates fat stores in the body and appetite by controlling the feeling of satiety. This hormone is secreted by the white adipose tissue and plays a role in the storage and mobilization of fatty acids. Mutations of the LEP gene have been associated with obesity in different populations; it is a multifactorial disease that constitutes a major public health problem. In this study,...

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Identifiers

PMID: 31871931
DOI: 10.1155/2019/1832084
PMCID: PMC6913293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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