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Article

A novel mutation in leptin gene is associated with severe obesity in Chinese individuals.

BioMed research international - 1 Jan 2014

Zhao Yue, Hong Nanchao, Liu Xiao, Wu Beibei, Tang Shanshan, Yang Jianjun, Hu Cheng, Jia Weiping

Abstract excerpt

Obesity is a clinical syndrome which is driven by interactions between multiple genetic and environmental factors. Monogenic obesity is a rare type of obesity which is caused by a mutation in a single gene. Patients with monogenic obesity may develop early onset of obesity and severe metabolic abnormalities. In this study, we screened mutations of LEP in a total of 135 Chinese individuals including 35 obese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24707501
DOI: 10.1155/2014/912052
PMCID: PMC3953508

Genes

LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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