Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Profilin1-Dependent F-Actin Assembly Controls Division of Apical Radial Glia and Neocortex Development.

Cerebral cortex (New York, N.Y. : 1991) - 18 May 2020

Kullmann Jan A, Meyer Sophie, Pipicelli Fabrizia, Kyrousi Christina, Schneider Felix, Bartels Nora, Cappello Silvia, Rust Marco B

Abstract excerpt

Neocortex development depends on neural stem cell proliferation, cell differentiation, neurogenesis, and neuronal migration. Cytoskeletal regulation is critical for all these processes, but the underlying mechanisms are only poorly understood. We previously implicated the cytoskeletal regulator profilin1 in cerebellar granule neuron migration. Since we found profilin1 expressed throughout mouse neocortex...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Actins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Division

Share to Cell Proliferation

Share to Neocortex

Share to Neural Stem Cells

Share to Neurogenesis

Share to Profilins

Source

Identifiers

PMID: 31867667
DOI: 10.1093/cercor/bhz321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Profilin1-Dependent F-Actin Assembly Controls Division of Apical Radial Glia and Neocortex Development.PMID 31867667Read ↗

Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons.Semantic proximity Read ↗

Morphological and functional aspects of progenitors perturbed in cortical malformationsSemantic proximity Read ↗

Purkinje cell loss and motor coordination defects in profilin1 mutant mice.Semantic proximity Read ↗

A cell fate decision map reveals abundant direct neurogenesis in the human developing neocortexSemantic proximity Read ↗

Foxp1 controls neural stem cell competence and bias towards deep layer cortical fatesSemantic proximity Read ↗

Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice.Semantic proximity Read ↗

ARHGEF6-dependent cytoskeletal regulation underlies a conserved program of forebrain interneuron developmentSemantic proximity Read ↗

Pax6 controls radial glia differentiation in the cerebral cortex.Semantic proximity Read ↗

Molecular mechanisms of neuronal migration disorders, quo vadis?Semantic proximity Read ↗

Regulation of neuronal progenitor delamination by dynein-driven post-Golgi apical transportSemantic proximity Read ↗

Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.Semantic proximity Read ↗

Molecular analysis of the midbrain dopaminergic niche during neurogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.