Article
Pax6 controls radial glia differentiation in the cerebral cortex.
Neuron - 1 Nov 1998
Götz M, Stoykova A, Gruss P
Abstract excerpt
Radial glia cells perform a dual function in the developing nervous system as precursor cells and guides for migrating neurons. We show here that during forebrain neurogenesis, the transcription factor Pax6 is specifically localized in radial glia cells of the cortex but not of the basal telencep...
Topics
- Animals
- Cell Differentiation
- Cells, Cultured
- Cerebral Cortex
- DNA-Binding Proteins
- Embryo, Mammalian
- Eye Proteins
- Growth Substances
- Homeodomain Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Mutant Strains
- Mutation
- Neuroglia
- PAX6 Transcription Factor
- Paired Box Transcription Factors
- Repressor Proteins