Article

Regulation of neuronal progenitor delamination by dynein-driven post-Golgi apical transport

2021-07-24

Abstract excerpt

Radial glial (RG) cells are the neural stem cells of the developing neocortex. Apical RG (aRG) cells can delaminate to generate basal RG (bRG) cells, a cell type associated with human brain expansion. Here, we report that this delamination is regulated by the post-Golgi secretory pathway. Using in situ subcellular live imaging, we show that post-Golgi transport of RAB6+ vesicles occurs toward the minus ends of mi...

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Identifiers and source

Literature Corpus work: 020733d1-a9b1-5128-b7d8-77418d78591c
DOI: 10.1101/2021.07.23.453475

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