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Article

Parameter, noise, and tree topology effects in tumor phylogeny inference.

BMC medical genomics - 23 Dec 2019

Tomlinson Kiran, Oesper Layla

Abstract excerpt

BACKGROUND: Accurate inference of the evolutionary history of a tumor has important implications for understanding and potentially treating the disease. While a number of methods have been proposed to reconstruct the evolutionary history of a tumor from DNA sequencing data, it is not clear how aspects of the sequencing data and tumor itself affect these reconstructions. METHODS: We investigate when and how well...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31865909
DOI: 10.1186/s12920-019-0626-0
PMCID: PMC6927103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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