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Article

Mg2+-ATP Sensing in CNNM, a Putative Magnesium Transporter.

Structure (London, England : 1993) - 3 Mar 2020

Chen Yu Seby, Kozlov Guennadi, Fakih Rayan, Yang Meng, Zhang Zhidian, Kovrigin Evgenii L, Gehring Kalle

Abstract excerpt

The family of cystathionine-β-synthase (CBS)-pair domain divalent metal cation transport mediators (CNNMs) is composed of four integral membrane proteins associated with Mg2+ transport. Structurally, CNNMs contain large cytosolic regions composed of a CBS-pair and a cyclic nucleotide-binding homology (CNBH) domain. How these regulate Mg2+ transport activity is unknown. Here, we determined the crystal structures...

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Identifiers

PMID: 31864811
DOI: 10.1016/j.str.2019.11.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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