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Article

Dimerization of the CNNM extracellular domain.

Protein science : a publication of the Protein Society - 1 Feb 2024

Shahsavan Ashkan, Lee Emma L, Illes Katalin, Kozlov Guennadi, Gehring Kalle

Abstract excerpt

Cystathionine- β $$ \beta $$ -synthase (CBS)-pair domain divalent metal cation transport mediators (CNNMs) are an evolutionarily conserved family of magnesium transporters. They mediate magnesium homeostasis directly by transport of Mg2+ ions and indirectly by regulation of the transient receptor potential ion channel subfamily M member 7 (TRPM7). Here, we report the crystal structure of the extracellular domain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38149326
DOI: 10.1002/pro.4860
PMCID: PMC10804811

Genes

CNNM4
CBS
CNNM2
TRPM7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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