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Article

Multiplexed discrimination of microRNA single nucleotide variants through triplex molecular beacon sensors.

Chemical communications (Cambridge, England) - 5 Jul 2018

Wu Xiaoyuan, Guo Bingyuan, Sheng Yingying, Zhang Yun, Wang Jin, Peng Shuchuan, Liu Lei, Wu Hai-Chen

Abstract excerpt

Herein, we develop a new nanopore sensing strategy for the selective detection of microRNAs and single nucleotide variants (SNVs) based on triplex molecular beacon sensors. This sensing system shows very high specificity in discriminating microRNA SNVs and can be applied for the simultaneous detection of several microRNAs of the same family in a mixture.

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PMID: 29938280
DOI: 10.1039/c8cc03574a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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