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Article

Clinical Relevance of CYP2D6 Polymorphisms in Patients of an Austrian Medical Practice: A Family Practice-Based Observational Study

20 Dec 2019

Abstract excerpt

BACKGROUND: Around 20-30% of all prescribed drugs are estimated to be metabolised by the cytochrome P450 (CYP) 2D6 enzyme. In a medical practice, it is usually not known whether a patient is a poor, intermediate, normal or ultra-rapid metaboliser for CYP2D6-metabolised drugs. OBJECTIVE: This study aims to explore the clinical relevance and the extent of hazardous prescriptions by analysing the metaboliser status...

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PMID: 31863305
DOI: 10.1007/s40801-019-00177-4

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