Article
Metabolic syndrome but not genetic polymorphisms known to induce NAFLD predicts increased total mortality in subjects with NAFLD (OPERA study).
Scandinavian journal of clinical and laboratory investigation - 1 Jan 2000
Käräjämäki Aki Juhani, Hukkanen Janne, Kauma Heikki, Kesäniemi Y Antero, Ukkola Olavi
Abstract excerpt
Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). However, knowledge about how these affect the mortality of subjects with NAFLD is scarce. Therefore, we investigated the impact of MetS, PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 on overall and cardiovascular disease (CVD)...