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Article

PNPLA3 genotype and fibrosis-4 index predict cardiovascular diseases of Japanese patients with histopathologically-confirmed NAFLD.

BMC gastroenterology - 19 Nov 2021

Akuta Norio, Kawamura Yusuke, Arase Yasuji, Saitoh Satoshi, Fujiyama Shunichiro, Sezaki Hitomi, Hosaka Tetsuya, Kobayashi Masahiro, Kobayashi Mariko, Suzuki Yoshiyuki, Suzuki Fumitaka, Ikeda Kenji, Kumada Hiromitsu

Abstract excerpt

BACKGROUND: Reliable noninvasive predictors of the top three causes of death [cardiovascular diseases (CVDs), malignancies, and liver-related events in patients with non-alcoholic fatty liver disease (NAFLD)] have not yet been determined. METHODS: We retrospectively investigated the incidence of three complications [CVDs, malignancy (except for liver cancer), and liver-related events] in 477 Japanese patients...

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Identifiers

PMID: 34798835
DOI: 10.1186/s12876-021-02020-z
PMCID: PMC8603578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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