Article
NAFLD-related gene polymorphisms and all-cause and cause-specific mortality in an Asian population: the Shanghai Changfeng Study.
Alimentary pharmacology & therapeutics - 1 Mar 2022
Xia Mingfeng, Ma Shuai, Huang Qingxia, Zeng Hailuan, Ge Jieyu, Xu Wenjie, Wu Qi, Wu Li, Li Xiaoming, Ma Hui, Chen Lingyan, Li Qian, Aleteng Qiqige, Hu Yu, He Wanyuan, Pan Baishen, Lin Huandong, Zheng Yan, Wang Sijia, Tang Huiru, Gao Xin
Abstract excerpt
BACKGROUND: The PNPLA3 and TM6SF2 gene variants have been found to cause NAFLD with a favourable cardiovascular risk profile. AIMS: To investigate the effects of the NAFLD risk alleles on the all-cause and cause-specific mortality in 5581 Chinese adults. METHODS: The genome-wide genotypes were detected using a genotyping array and serum lipoprotein profiles were examined using 1H NMR platform. Liver fat content...
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