Article
No association of NAFLD-related polymorphisms in PNPLA3 and TM6SF2 with all-cause and cardiovascular mortality in an Austrian population study.
Wiener klinische Wochenschrift - 1 May 2024
Semmler Georg, Balcar Lorenz, Wernly Sarah, Datz Leonora, Semmler Marie, Rosenstatter Lea, Stickel Felix, Aigner Elmar, Wernly Bernhard, Datz Christian
Abstract excerpt
BACKGROUND AND AIMS: Single-nucleotide-polymorphisms in PNPLA3-rs738409 and the TM6SF2-rs58542926, associated with metabolic-dysfunction-associated fatty liver disease (MAFLD), have been discussed as potentially protective for cardiovascular diseases. Therefore, we aimed to study the associations of PNPLA3/TM6SF2 variants with MAFLD and cardiovascular risk in a population-based sample of asymptomatic patients....
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