Article
"Renal Cell Carcinoma With Leiomyomatous Stroma" Harbor Somatic Mutations of TSC1, TSC2, MTOR, and/or ELOC (TCEB1): Clinicopathologic and Molecular Characterization of 18 Sporadic Tumors Supports a Distinct Entity.
The American journal of surgical pathology - 1 May 2020
Shah Rajal B, Stohr Bradley A, Tu Zheng Jin, Gao Yuan, Przybycin Christopher G, Nguyen Jane, Cox Roni M, Rashid-Kolvear Fariborz, Weindel Michael D, Farkas Daniel H, Trpkov Kiril, McKenney Jesse K
Abstract excerpt
Renal cell carcinoma with (angio) leiomyomatous stroma (RCCLMS) is included as a provisional entity in the 2016 World Health Organization (WHO) classification of renal epithelial neoplasia; however, debate remains whether it represents a distinct entity or a heterogenous group of renal cell carcinomas (RCCs) with overlapping morphology. Also, its relationship to similar tumors occurring in the setting of tuberous...
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