Article
Renal Cell Carcinoma in Tuberous Sclerosis Complex.
Genes - 8 Oct 2021
Henske Elizabeth P, Cornejo Kristine M, Wu Chin-Lee
Abstract excerpt
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder in which renal manifestations are prominent. There are three major renal lesions in TSC: angiomyolipomas, cysts, and renal cell carcinoma (RCC). Major recent advances have revolutionized our understanding of TSC-associated RCC, including two series that together include more than 100 TSC-RCC cases, demonstrating a mean age at onset of about 36...
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