Article
Renal cell carcinoma with leiomyomatous stroma--further immunohistochemical and molecular genetic characteristics of unusual entity.
Annals of diagnostic pathology - 1 Oct 2014
Peckova Kvetoslava, Grossmann Petr, Bulimbasic Stela, Sperga Maris, Perez Montiel Delia, Daum Ondrej, Rotterova Pavla, Kokoskova Bohuslava, Vesela Pavla, Pivovarcikova Kristyna, Bauleth Kevin, Branzovsky Jindrich, Dubova Magdalena, Hora Milan, Michal Michal, Hes Ondrej
Abstract excerpt
UNLABELLED: Renal cell carcinoma (RCC) with leiomyomatous stroma (RCCLS) is a recently recognized entity with indolent biological behavior. The diagnostic implication of absence/presence of VHL gene mutation, VHL hypermethylation, or/and loss of heterozygosity of chromosome 3p (LOH 3p) is widely discussed. Criteria for establishing a diagnosis of RCCLS are still lacking. Fifteen RCCLSs were retrieved from our...
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