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Article

Are Sporadic Eosinophilic Solid and Cystic Renal Cell Carcinomas Characterized by Somatic Tuberous Sclerosis Gene Mutations?

The American journal of surgical pathology - 1 Jul 2018

Parilla Megan, Kadri Sabah, Patil Sushant A, Ritterhouse Lauren, Segal Jeremy, Henriksen Kammi J, Antic Tatjana

Abstract excerpt

Eosinophilic solid and cystic renal cell carcinomas (ESC RCC) is a rare, unique tumor type not yet included in the World Health Organization classification of renal neoplasia. Separately, RCCs found in patients with tuberous sclerosis complex (TSC) have recently been categorized into 3 morphologic groups: RCC with a tubulopapillary architecture separated by smooth muscle stroma, chromophobe-like, and...

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Biomarkers, Tumor
Biopsy
Carcinoma, Renal Cell
Eosinophilia
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kidney Neoplasms

Neoplasms, Cystic, Mucinous, and Serous

Tuberous Sclerosis Complex 2 Protein

Source

Identifiers

PMID: 29668487
DOI: 10.1097/PAS.0000000000001067

Genes

TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Are Sporadic Eosinophilic Solid and Cystic Renal Cell Carcinomas Characterized by Somatic Tuberous Sclerosis Gene Mutations?PMID 29668487Read ↗

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Eosinophilic vacuolated tumor (EVT) of kidney demonstrates sporadic TSC/MTOR mutations: next-generation sequencing multi-institutional study of 19 cases.Semantic proximity Read ↗

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