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Article

A powerful fine-mapping method for transcriptome-wide association studies.

Human genetics - 1 Feb 2020

Wu Chong, Pan Wei

Abstract excerpt

Transcriptome-wide association studies (TWAS) have been recently applied to successfully identify many novel genes associated with complex traits. While appealing, TWAS tend to identify multiple significant genes per locus, and many of them may not be causal due to confounding through linkage disequilibrium (LD) among SNPs. Here we introduce a powerful fine-mapping method that prioritizes putative causal genes by...

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Identifiers

PMID: 31844974
DOI: 10.1007/s00439-019-02098-2
PMCID: PMC6983348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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