Article
R-From-T as a Common Mechanism of Arrhythmia Initiation in Long QT Syndromes.
Circulation. Arrhythmia and electrophysiology - 1 Dec 2019
Liu Michael B, Vandersickel Nele, Panfilov Alexander V, Qu Zhilin
Abstract excerpt
BACKGROUND: Long QT syndromes (LQTS) arise from many genetic and nongenetic causes with certain characteristic ECG features preceding polymorphic ventricular tachyarrhythmias (PVTs). However, how the many molecular causes result in these characteristic ECG patterns and how these patterns are mechanistically linked to the spontaneous initiation of PVT remain poorly understood. METHODS: Anatomic human ventricle and...
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