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Article

Trigger-specific ion-channel mechanisms, risk factors, and response to therapy in type 1 long QT syndrome.

Heart rhythm - 1 Jan 2012

Goldenberg Ilan, Thottathil Princy, Lopes Coeli M, Moss Arthur J, McNitt Scott, O-Uchi Jin, Robinson Jennifer L, Zareba Wojciech, Ackerman Michael J, Kaufman Elizabeth S, Towbin Jeffrey A, Vincent Michael, Barsheshet Alon

Abstract excerpt

BACKGROUND: Arrhythmic events in long-QT syndrome type 1 (LQT1) may be associated with exercise, acute arousal, or rest/sleep. OBJECTIVES: We aimed to identify trigger-specific risk factors for cardiac events in patients with LQT1. METHODS: The study population comprised 721 genetically confirmed patients with LQT1 from the US portion of the International LQTS Registry. Multivariate analysis was used to assess...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21871251
DOI: 10.1016/j.hrthm.2011.08.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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