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Article

Architectural T-Wave Analysis and Identification of On-Therapy Breakthrough Arrhythmic Risk in Type 1 and Type 2 Long-QT Syndrome.

Circulation. Arrhythmia and electrophysiology - 1 Nov 2017

Sugrue Alan, Rohatgi Ram K, Noseworthy Peter A, Kremen Vaclav, Bos J Martijn, Qiang Bo, Sapir Yehu, Attia Zachi I, Scott Christopher G, Brady Peter, Asirvatham Samuel J, Friedman Paul A, Ackerman Michael J

Abstract excerpt

BACKGROUND: Although the hallmark of long-QT syndrome (LQTS) is abnormal cardiac repolarization, there are varying degrees of phenotypic expression and arrhythmic risk. Our aim was to evaluate the performance of a morphological T-wave analysis program in defining breakthrough LQTS arrhythmic risk beyond the QTc value. METHODS AND RESULTS: We analyzed 407 genetically confirmed patients with LQT1 (n=246; 43% men)...

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PMID: 29141844
DOI: 10.1161/CIRCEP.117.005648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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